Tetrahydrofuran → 2-(4-chloro-5-cyanopyrimidin-2-ylamino)-2-methyl-N-(2,2,2-trifluoroethyl)propanamide

HRID 118953Notes

Reaction equation

HRID 118953 reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH:23]([N:24]([CH2:25][CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]#[N:10])[c:6]([Cl:8])[n:7]1.[NH2:11][C:12]([C:13](=[O:14])[NH:15][CH2:16][C:17]([F:18])([F:19])[F:20])([CH3:21])[CH3:22]>>[c:2]1([NH:11][C:12]([C:13](=[O:14])[NH:15][CH2:16][C:17]([F:18])([F:19])[F:20])([CH3:21])[CH3:22])[n:3][cH:4][c:5]([C:9]#[N:10])[c:6]([Cl:8])[n:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 140269072,4-Dichloro-5-cyanopyrimidineHCID 61264399Propanamide, 2-amino-2-methyl-N-(2,2,2-trifluoroethyl)-

Product 1

HCID 594143192-(4-chloro-5-cyanopyrimidin-2-ylamino)-2-methyl-N-(2,2,2-trifluoroethyl)propanamide

Sources & evidence

ORD record
ord-7c66071690104ddb81e4aaed02a0cca7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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