Dimethyl Sulfoxide → Tert-butyl 3-formylazetidine-1-carboxylate

HRID 119257Notes

Reaction equation

HRID 119257 reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:31][CH2:32][Cl:33].[OH:11][CH2:12][CH:13]1[CH2:14][N:15]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:16]1>>[O:11]=[CH:12][CH:13]1[CH2:14][N:15]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:16]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 10583745tert-Butyl 3-(hydroxymethyl)azetidine-1-carboxylate

Product 1

HCID 10726182Tert-butyl 3-formylazetidine-1-carboxylate

Sources & evidence

ORD record
ord-a81e2e2f4bee4f059171f03d2ea4cbff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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