反应详情

First, 25 g of 2-methylthiocycloheptimidazole was added to 100 ml of anisole, and stirred under ice cooling. Then, 28 g of methyl trifluoromethanesulfonate was added dropwise and stirred under ice cooling. The mixture was further stirred at room temperature for 2 hours and 30 minutes, 200 ml of ethyl acetate was added thereto, and deposited crystals were filtered and dried.

1. stirringstirred under ice cooling
2. stirringThe mixture was further stirred at room temperature for 2 hours and 30 minutes
3. filtrationwere filtered
4. customdried