Anisole → HCID 178494296, compound

HRID 1194291Notes

Reaction equation

HRID 1194291 reaction equation
[CH3:1][O:2][C:3]1[N:4]=[C:5]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=[C:6]2[N:7]=1.[C:13]1(OC)C=CC=CC=1.[F:21][C:22]([F:29])([F:28])[S:23]([O:26]C)(=[O:25])=[O:24]>C(OCC)(=O)C>[F:21][C:22]([F:29])([F:28])[S:23]([O-:26])(=[O:25])=[O:24].[CH3:1][O:2][CH:3]1[NH+:4]=[C:5]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=[C:6]2[N:7]1[CH3:13]

Participants

5

Reactant 3

HCID 7519AnisoleHCID 9526Methyl triflateHCID 200643812-Methoxycyclohepta[d]imidazole

Product 1

HCID 178494296HCID 178494296, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

First, 0.9 g of 2-methoxycycloheptimidazole was added to 5 ml of anisole, and 1.1 g of methyl trifluoromethanesulfonate was added dropwise. After being stirred at room temperature for one hour, 30 ml of ethyl acetate was added, and deposited crystals were collected by filtration and dried.

Workup

  1. additionwas added dropwise
  2. filtrationwere collected by filtration
  3. customdried

Sources & evidence

ORD record
ord-2384df325e4c40b98c490d26653142cf
Source dataset
uspto-grants-1989_03
Patent number
US04814265

Reaction notes

Loading…