Anisole → 2-Chloro-3-methylcycloheptimidazolium trifluoromethanesulfonate

HRID 1194294Notes

Reaction equation

HRID 1194294 reaction equation
[Cl:1][C:2]1[N:3]=[C:4]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=[C:5]2[N:6]=1.[C:12]1(OC)C=CC=CC=1.[F:20][C:21]([F:28])([F:27])[S:22]([O:25]C)(=[O:24])=[O:23]>C(OCC)(=O)C>[F:20][C:21]([F:28])([F:27])[S:22]([O-:25])(=[O:24])=[O:23].[Cl:1][CH:2]1[NH+:3]=[C:4]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=[C:5]2[N:6]1[CH3:12]

Participants

5

Reactant 3

HCID 7519AnisoleHCID 9526Methyl triflateHCID 200643702-Chlorocycloheptimidazole

Product 1

HCID 1784798762-Chloro-3-methylcycloheptimidazolium trifluoromethanesulfonate

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2-Chlorocycloheptimidazole (0.78 g) was added to 4 ml of anisole, 0.93 g of methyl trifluoromethanesulfonate was added dropwise thereto, and the mixture was stirred at room temperature for 40 minutes. Then, 50 ml of ethyl acetate was added to the reaction solution, and deposited crystals were collected by filtration and dried.

Workup

  1. additionwas added dropwise
  2. filtrationwere collected by filtration
  3. customdried

Sources & evidence

ORD record
ord-5add8081ce714f8b9222896e887d5fb5
Source dataset
uspto-grants-1989_03
Patent number
US04814265

Reaction notes

Loading…