Hydrazine hydrate (1:1) → HCID 21249171, compound

HRID 1194674Notes

Reaction equation

HRID 1194674 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=O)[CH:10]([CH3:15])[CH2:11][C:12](O)=[O:13])=[CH:5][CH:4]=1.O.[NH2:18][NH2:19]>C(O)(C)C>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]([CH3:15])[CH2:11][C:12](=[O:13])[NH:18][N:19]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 13693406HCID 13693406, compound

Product 1

HCID 21249171HCID 21249171, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

2.3 g (0.01 mole) of 4-(4-methylthio-phenyl)-4-oxo-3-methyl-butyric acid and 1 ml of hydrazine hydrate are heated under reflux in 20 ml of isopropanol for 2 hour. After the mixture has been cooled, the product is filtered off with suction and dried.

Workup

  1. temperatureAfter the mixture has been cooled
  2. filtrationthe product is filtered off with suction
  3. customdried

Sources & evidence

ORD record
ord-fdb03b77d58940cf8d186e5619f473b4
Source dataset
uspto-grants-1989_03
Patent number
US04816454

Reaction notes

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