Hydrogen Bromide → 2-amino-4-(4-fluorophenyl)-5-[2-[4-(5-fluoro-1H-benzotriazol-1-yl)piperidin-1-yl]ethyl]thiazole
Reaction equation
[BrH:1].[CH3:43][OH:44].[CH3:45][CH2:46][OH:47].[CH:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH2:39][CH3:40])([CH3:41])[CH3:42].[F:18][c:19]1[cH:20][c:21]2[c:22]([n:23]([CH:26]3[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]3)[n:24][n:25]2)[cH:32][cH:33]1.[NH2:2][c:3]1[s:4][c:5]([CH2:15][CH2:16][Br:17])[c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[n:7]1>>[NH2:2][c:3]1[s:4][c:5]([CH2:15][CH2:16][N:29]2[CH2:28][CH2:27][CH:26]([n:23]3[c:22]4[c:21]([cH:20][c:19]([F:18])[cH:33][cH:32]4)[n:25][n:24]3)[CH2:31][CH2:30]2)[c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-be69014f786c437992d1b86483cc2e65
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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