Thionyl Chloride → HCID 14832336, compound

HRID 1195449Notes

Reaction equation

HRID 1195449 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]([C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][CH:27]=3)=[CH:21][CH:20]=2)([C:15]([F:18])([F:17])[F:16])[C:11]([F:14])([F:13])[F:12])=[CH:6][CH:5]=1)(O)=[O:2].S(Cl)([Cl:37])=O>CN(C)C=O>[Cl:37][C:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]([C:19]2[CH:24]=[CH:23][C:22]([O:25][C:26]3[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][CH:27]=3)=[CH:21][CH:20]=2)([C:15]([F:18])([F:17])[F:16])[C:11]([F:14])([F:13])[F:12])=[CH:6][CH:5]=1)=[O:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14832328HCID 14832328, compound

Product 1

HCID 14832336HCID 14832336, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

9.7 g (0.02 mol) of 2-(4-carboxyphenyl)-2-[4-(4-nitrophenoxy)phenyl]hexafluoropropane were suspended in 47 cm3 of thionyl chloride, a few drops of dimethylformamide were added, and the mixture was refluxed until evolution of gas was no longer observed. The thionyl chloride was removed by distillation, and the residue was recrystallized from acetonitrile.

Workup

  1. temperaturethe mixture was refluxed until evolution of gas
  2. customThe thionyl chloride was removed by distillation
  3. customthe residue was recrystallized from acetonitrile

Sources & evidence

ORD record
ord-de1705453aa645babb12665ed84d4b41
Source dataset
uspto-grants-1992_05
Patent number
US05110983

Reaction notes

Loading…