反应详情

102 g (0.75 mol) of 2-hydroxyacetophenone and 102 g (0.75 mol) of potassium carbonate in 500 ml of absolute ethanol are initially taken. 139 g (0.75 mol) of 2-methylbenzyl bromide are added dropwise and the mixture is refluxed for 10 h. The mixture is cooled and filtered under suction, after which the filtrate is evaporated down. The crude product is recrystallized from diethyl ether. 106 g (59%) of product are obtained as crystals (mp.=53°-55° C.).

1. temperaturethe mixture is refluxed for 10 h
2. temperatureThe mixture is cooled
3. filtrationfiltered under suction
4. customafter which the filtrate is evaporated down
5. customThe crude product is recrystallized from diethyl ether