1(2H)-Phthalazinone → HCID 19898932, compound

HRID 1196543Notes

Reaction equation

HRID 1196543 reaction equation
Cl.C[N:3]([CH2:15][CH2:16][N:17]1[N:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]1=[O:27])[CH2:4][CH2:5]C1C=CC([N+]([O-])=O)=CC=1.NC1C=CC(CCN(CCN2N=CC3C(=CC=CC=3)C2=O)C)=CC=1.C(N(CCCl)CC)C1C=CC=CC=1.C1(=O)C2C(=CC=CC=2)C=NN1.[H-].[Na+]>CN(C)C=O>[CH2:4]([NH:3][CH2:15][CH2:16][N:17]1[N:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[C:18]1=[O:27])[CH3:5]

Participants

7

Reactant 5

HCID 83941(2H)-PhthalazinoneHCID 24758Sodium hydrideHCID 31966Benzenemethanamine, N-(2-chloroethyl)-N-ethyl-HCID 19898931HCID 19898931, compoundHCID 19898945HCID 19898945, compound

Product 1

HCID 19898932HCID 19898932, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

N-Ethyl-2-(2H-phthalazin-1-on-2-yl)ethylamine was prepared similarly to the method of Preparation 1 parts (A) and (B) using N-benzyl-N-ethyl-2-chloroethylamine, 2H-phthalazin-1-one and sodium hydride in dimethylformamide.

Sources & evidence

ORD record
ord-05db63e2fa514bc79343971ea6ab4ca2
Source dataset
uspto-grants-1992_05
Patent number
US05114952

Reaction notes

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