Chloral Hydrate → HCID 19896175, compound

HRID 1196744Notes

Reaction equation

HRID 1196744 reaction equation
[Cl:1][C:2]([Cl:7])([Cl:6])[CH:3]([OH:5])[OH:4].[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[CH3:16][C:17]1[CH:22]=[CH:21][C:20](S(O)(=O)=O)=[CH:19][CH:18]=1>C1C=CC=CC=1>[CH2:8]([O:4][CH:3]([O:5][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C:2]([Cl:7])([Cl:6])[Cl:1])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

5

Reactant 3

HCID 2707Chloral HydrateHCID 6101p-Toluenesulfonic acidHCID 8129Heptanol

Product 1

HCID 19896175HCID 19896175, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 5 g of chloral hydrate, 12 g of heptanol, 0.1 g of 4-methyl-benzene-sulphonic acid and 50 ml of benzene is kept at reflux temperature and the formed water is separated by means of a Dean-Stark apparatus. Afater a reaction time of 9 hours the benzene is washed with a sodium hydrogen carbonate solution and water, dried on magnesium sulfate, then vacuum distilled.

Workup

  1. temperatureat reflux temperature
  2. customthe formed water is separated by means of a Dean-Stark apparatus
  3. washAfater a reaction time of 9 hours the benzene is washed with a sodium hydrogen carbonate solution and water
  4. customdried on magnesium sulfate
  5. distillationvacuum distilled

Sources & evidence

ORD record
ord-f50f4b70982647389cdd19c71df973c5
Source dataset
uspto-grants-1992_05
Patent number
US05116402

Reaction notes

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