1-Butanol → HCID 12504164, compound

HRID 1196747Notes

Reaction equation

HRID 1196747 reaction equation
O.[Cl:2][C:3]([Cl:8])([Cl:7])[CH:4]([OH:6])[OH:5].[CH2:9](O)[CH2:10][CH2:11][CH3:12].[CH3:14][C:15]1C=CC(S(O)(=O)=O)=[CH:17][CH:16]=1>C1C=CC=CC=1>[CH2:9]([O:5][CH:4]([O:6][CH2:14][CH2:15][CH2:16][CH3:17])[C:3]([Cl:8])([Cl:7])[Cl:2])[CH2:10][CH2:11][CH3:12]

Participants

6

Reactant 4

HCID 2631-ButanolHCID 962WaterHCID 2707Chloral HydrateHCID 6101p-Toluenesulfonic acid

Product 1

HCID 12504164HCID 12504164, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Into an apparatus supplied with a Dean-Stark water separator 7 g of chloral hydrate, 10 g of butyl alcohol, 0.1 g of 4-methyl-benzene-sulphonic acid and 50 ml of benzene are weighed. The mixture is heated on a water-bath and the water separation is continued for 10 hours. The benzene is washed with water and sodium hydrogen carbonate, then distilled off and the product is vacuum distilled.

Workup

  1. temperatureThe mixture is heated on a water-bath
  2. customthe water separation
  3. washThe benzene is washed with water and sodium hydrogen carbonate
  4. distillationdistilled off
  5. distillationdistilled

Sources & evidence

ORD record
ord-010456fb483541458293f0b94095fbe3
Source dataset
uspto-grants-1992_05
Patent number
US05116402

Reaction notes

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