Chloral Hydrate → HCID 19896181, compound

HRID 1196750Notes

Reaction equation

HRID 1196750 reaction equation
[Cl:1][C:2]([Cl:7])([Cl:6])[CH:3]([OH:5])[OH:4].[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].C[C:16]1[CH:21]=[CH:20][C:19](S(O)(=O)=O)=[CH:18][CH:17]=1>C1C=CC=CC=1>[CH2:8]([O:4][CH:3]([O:5][CH2:20][CH2:21][CH2:16][CH2:17][CH2:18][CH3:19])[C:2]([Cl:7])([Cl:6])[Cl:1])[CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Participants

5

Reactant 3

HCID 2707Chloral HydrateHCID 6101p-Toluenesulfonic acidHCID 81031-Hexanol

Product 1

HCID 19896181HCID 19896181, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 5 g of chloral hydrate, 11 g of hexanol, 0.1 g of 4-methyl-benzene-sulphonic acid and 50 ml of benzene is kept at reflux temperature and the formed water is separated by means of a Dean-Stark apparatus. After a reaction time of 9 hours the benzene is washed with a sodium hydrogen carbonate solution and water, dried on magnesium sulfate, then distilled in vacuo.

Workup

  1. temperatureat reflux temperature
  2. customthe formed water is separated by means of a Dean-Stark apparatus
  3. washAfter a reaction time of 9 hours the benzene is washed with a sodium hydrogen carbonate solution and water
  4. customdried on magnesium sulfate
  5. distillationdistilled in vacuo

Sources & evidence

ORD record
ord-b10845288913446db1bcaf2d78129115
Source dataset
uspto-grants-1992_05
Patent number
US05116402

Reaction notes

Loading…