Hydrochloric Acid → HCID 57124953, compound

HRID 1196962Notes

Reaction equation

HRID 1196962 reaction equation
[O:1]=[C:2]1[C:6](=[C:7]([CH3:23])[CH:8]=[CH:9][C:10]2[CH:22]=[CH:21][C:13]([O:14][CH2:15][C:16]([O:18]CC)=[O:17])=[CH:12][CH:11]=2)[S:5][C:4](=[S:24])[NH:3]1.[OH-].[Na+].Cl>O>[O:1]=[C:2]1[C:6](=[C:7]([CH3:23])[CH:8]=[CH:9][C:10]2[CH:22]=[CH:21][C:13]([O:14][CH2:15][C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)[S:5][C:4](=[S:24])[NH:3]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 57311210HCID 57311210, compound

Product 1

HCID 57124953HCID 57124953, compoundYield 54%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 0.12 g of Isomer A of ethyl 4-[3-(4-oxo-2-thioxo-5-thiazolidinylidene)-1-butenyl]phenoxyacetate, 5 ml of water and 1 ml of 5% sodium hydroxide solution was stirred at room temperature for one hour. 10% hydrochloric acid was added to the mixture and the precipitated crystals were collected by filtration and washed with methanol to give Isomer A (54% yield) of 4-[3-(4-oxo-2-thioxo-5-thiazolidinylidene)-1-butenyl]phenoxyacetic acid.

Workup

  1. filtrationthe precipitated crystals were collected by filtration
  2. washwashed with methanol

Sources & evidence

ORD record
ord-220c04e7455a4ca18c6ba01f36851d2b
Source dataset
uspto-grants-1992_05
Patent number
US05116855

Reaction notes

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