反应详情

Thiophene (50 mmol), formaldehyde (10 mmol) and 4-isopropylbenzamide (10 mmol}were stirred in formic acid (10 ml) at 20° C. for four hours and treated in the same manner as in Example 2 to obtain N-(2-thienylmethyl)-4-isopropylbenzamide. Yield: 80%.

1. additiontreated in the same manner as in Example 2