Triethylamine → HCID 19107030, compound

HRID 1197539Notes

Reaction equation

HRID 1197539 reaction equation
[CH:1]1[C:10]2[C:9]3(C(O)=O)[CH2:11][CH2:12][CH2:13][CH2:14][CH:8]3[CH2:7][O:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.C1(P(N=[N+]=[N-])(C2C=CC=CC=2)=[O:25])C=CC=CC=1.C([N:37]([CH2:40]C)CC)C>C1(C)C=CC=CC=1>[N:37]([C:9]12[CH2:11][CH2:12][CH2:13][CH2:14][CH:8]1[CH2:7][O:6][C:5]1[CH:4]=[CH:3][CH:2]=[CH:1][C:10]2=1)=[C:40]=[O:25]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 199401P,P-Diphenylphosphinic azideHCID 19107117HCID 19107117, compound

Product 1

HCID 19107030HCID 19107030, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of the compound from Example 70 (1.0 g, 4.30 mmol) and diphenylphosphorylazide (1.3 g, 4.7 mmol) in 1.1 ml triethylamine and toluene was refluxed for 15 hours. Workup and silica gel chromatography gave the title compound (0.71 g) as a clear oil.

Sources & evidence

ORD record
ord-8a0a0c7f52174ef8bcbdf8f97b36776a
Source dataset
uspto-grants-1994_01
Patent number
US05276053

Reaction notes

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