2-Pentadecanone → 3-oxo-N-(2,4,6-trimethoxyphenyl)pentadecanamide

HRID 1198055Notes

Reaction equation

[CH3:1][C:2](=[O:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]C.[CH3:17][O:18][C:19]1[CH:24]=[C:23]([O:25][CH3:26])[CH:22]=[C:21]([O:27][CH3:28])[C:20]=1[N:29]=[C:30]=[O:31].C([N-]C(C)C)(C)C.[Li+]>>[O:16]=[C:2]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH2:1][C:30]([NH:29][C:20]1[C:19]([O:18][CH3:17])=[CH:24][C:23]([O:25][CH3:26])=[CH:22][C:21]=1[O:27][CH3:28])=[O:31]

Participants

Reactant 3

HCID 613032-Pentadecanone

HCID 2724682Lithium diisopropylamide

HCID 100818122,4,6-Trimethoxyphenyl isocyanate

Product 1

HCID 191055793-oxo-N-(2,4,6-trimethoxyphenyl)pentadecanamide

Procedure

The title compound was prepared from 2-pentadecanone (0.54 g, 0.0023 mol), 2,4,6-trimethoxyphenyl isocyanate (prepared from 2,4,6-trimethoxyaniline hydrochloride and phosgene (2.5 eq)) and lithium diisopropylamide (0.0023 mol) using the procedure described in Example 1.

Sources & evidence

ORD record: ord-e13e89574a66432f8b4cff609a0ab57c
Source dataset: uspto-grants-1994_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05278326

Reaction notes

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