Octane → 5-(Dodecylsulfonyl)pentan-2-one
Reaction equation
C(OC(=O)[CH2:5][C:6](=[O:25])[CH2:7][CH2:8][CH2:9][S:10]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])(=[O:12])=[O:11])C.CCCCCCCC>>[CH2:13]([S:10]([CH2:9][CH2:8][CH2:7][C:6](=[O:25])[CH3:5])(=[O:11])=[O:12])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]Participants
3
Procedure
The title compound was prepared from 6-(dodecylsulfonyl)-3-oxo-hexanoic acid ethyl ester (2.30 g, 0.005 mol), 1,4-diazebicyclo[2.2.2]octane (6.60 g, 0.058 mol) and zylenes (10.7 ML, 15.0 eq) using the procedure described in Example 3, Step B. 1H NMR (ppm, CDCl3): 0.85-0.90 (t, 3H), 1.17-1.43 (m, 20H), 1.76-1.88 (m, 2H), 2.03-2.14 (m, 2H), 2.16 (s, 3H) 2.96-3.03 (m, 4H),
Sources & evidence
- ORD record
- ord-ff09d9aaed0343fc96641a71b1d84e3f
- Source dataset
- uspto-grants-1994_01
- Patent number
- US05278326
Reaction notes
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