反应详情

The mixture consisting of 0.24 mole (57 g) of 6-benzyloxy-1-methylindole, 5.7 g of 10% palladium-on-charcoal, 114 ml of cyclohexene and 170 ml of 96% ethanol is heated for 30 minutes under reflux. The mixture is filtered hot to remove the catalyst. After evaporation of the filtrate under vacuum, an oil is obtained which, dissolved in isopropyl ether, gives the desired product after evaporation to dryness. It melts at 74° C.

1. temperatureis heated for 30 minutes
2. temperatureunder reflux
3. filtrationThe mixture is filtered hot
4. customto remove the catalyst
5. customAfter evaporation of the filtrate under vacuum
6. customan oil is obtained which