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HRID1198322

反应详情

EQUATION

反应方程式

HRID 1198322 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCCCOc1ccc(O)c(F)c1F
HCID19103433

4-Butoxy-2,3-difluorophenol

C10H12F2O2

结构：CCCCC[C@H]1CC[C@H](CBr)CC1
HCID178444389

未命名化合物

PRODUCTS

生成物

1
结构：CCCCC[C@H]1CC[C@H](COc2ccc(OCCCC)c(F)c2F)CC1
HCID178418677

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

0.1 mol of 2,3-difluoro-4-butoxyphenol, 0.11 mol of trans-4-pentylcyclohexylmethyl bromide and 0.11 mol of potassium carbonate are heated at 100° in 100 ml of dimethylformamide (DMF) for 16 hours. After cooling, the inorganic salts are filtered off with suction, the filtrate is concentrated and water is added. Extraction with methylene chloride gives 1-butoxy-2,3-difluoro-4-(trans-4-pentylcyclohexylmethoxy)benzene.

WORKUP

后处理

  1. temperatureAfter cooling
  2. filtrationthe inorganic salts are filtered off with suction
  3. concentrationthe filtrate is concentrated
  4. additionwater is added
  5. extractionExtraction with methylene chloride