Benzaldehyde → HCID 1551028, compound

HRID 1198634Notes

Reaction equation

HRID 1198634 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]1(=[O:14])[CH2:13][CH2:12][CH2:11][CH2:10]1>>[CH:1](=[C:10]1/[C:9](=[O:14])[CH2:13][CH2:12][CH2:11]/1)\[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 8452Cyclopentanone

Product 1

HCID 1551028HCID 1551028, compound

Procedure

The procedure was similar to that in Example 4 by reacting benzaldehyde with the morpholine enamine of cyclopentanone to give 2-(E)-benzylidene cyclopentanone. The melting point of this intermediate compound was determined to be 67°-69° C. A subsequent Mannich reaction yielded the 2-Dimethylaminomethyl-5-(E)-benzylidene cyclopentanone hydrochloride. The melting point of the product was determined to be 153°-155° C.

Sources & evidence

ORD record
ord-7b17cdb3643e4b8fb4fc178aafedf10e
Source dataset
uspto-grants-1994_01
Patent number
US05281622

Reaction notes

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