Potassium Carbonate → Bis(2-methylpropyl) dicarbonate

HRID 1198772Notes

Reaction equation

HRID 1198772 reaction equation
Cl[C:2]([O:4][CH2:5][CH:6]([CH3:8])[CH3:7])=[O:3].[C:9](=[O:12])([O-:11])[O-:10].[K+].[K+]>C(#N)C>[C:2]([O:12][C:9]([O:11][CH2:5][CH:6]([CH3:8])[CH3:7])=[O:10])([O:4][CH2:5][CH:6]([CH3:8])[CH3:7])=[O:3]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 62365Isobutyl chloroformate

Product 1

HCID 13678036Bis(2-methylpropyl) dicarbonate

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
40 °C

Procedure

Isobutyl chloroformate (136.76 g, 1.0 mol.) was added dropwise to a stirred mixture of powered, anhydrous potassium carbonate (77 g, 0.56 mol) in acetonitrile at such a rate as to maintain a reaction temperature of 40° C. The reaction mixture was stirred for six (6) hours at ambient temperature and then allowed to stand overnight prior to work-up. The crude product was purified by vacuum distillation, and the fraction collected between 58° and 62° C. at 0.05-0.10 mmHg was found to be di-isobutyl dicarbonate. YIELD=86.93 g=80%.

Workup

  1. distillationThe crude product was purified by vacuum distillation
  2. customthe fraction collected between 58° and 62° C. at 0.05-0.10 mmHg

Sources & evidence

ORD record
ord-0f73b8e265fb46ef97bb436d21bb0c9f
Source dataset
uspto-grants-1994_01
Patent number
US05281743

Reaction notes

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