Hydrogen Peroxide → HCID 15634753, compound

HRID 1198989Notes

Reaction equation

HRID 1198989 reaction equation
[CH3:1][C:2]1[C:3]([NH2:16])=[C:4]([CH:13]=[CH:14][CH:15]=1)[C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:6].OO>C(O)(=O)C>[CH3:1][C:2]1[C:3]2[C:4](=[C:5]([C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)[O:6][N:16]=2)[CH:13]=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 12290094Methanone, (2-amino-3-methylphenyl)phenyl-

Product 1

HCID 15634753HCID 15634753, compoundYield 49%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 8.4 g (0.04 mole) of 3-methyl-2-aminobenzophenone, 150 ml of acetic acid and 40 ml of 30% hydrogen peroxide was allowed to stand at ambient temperature for 3 days and the resulting solution was poured into 800 ml of ice-water mixture. The solid which precipitated was collected by filtration, washed with water and dried. This solid was recrystallized twice from isopropanol to yield 4.1 g (49%) of tan crystals, m.p. 73°-75° C.

Workup

  1. customThe solid which precipitated
  2. filtrationwas collected by filtration
  3. washwashed with water
  4. customdried
  5. customThis solid was recrystallized twice from isopropanol

Sources & evidence

ORD record
ord-1b9ff6e08b6b4b9bb06fb92b9d6a3cac
Source dataset
uspto-grants-1990_02
Patent number
US04898874

Reaction notes

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