m-Chloroperbenzoic acid → N-tert-Butyl-a-phenylnitrone

HRID 1199089Notes

Reaction equation

HRID 1199089 reaction equation
[CH2:1]([NH:8][C:9]([CH3:12])([CH3:11])[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1C=C(C=CC=1)C(OO)=[O:18]>C(Cl)Cl>[C:9]([N+:8]([O-:18])=[CH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)([CH3:12])([CH3:11])[CH3:10]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 76908N-(1,1-Dimethylethyl)benzenemethanamine

Product 1

HCID 4390N-tert-Butyl-a-phenylnitrone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the general procedure of Example 1, N-benzyl-N-tert-butylamine is oxidized using a solution of 3-chloroperoxybenzoic acid dissolved in methylene chloride to give N-tert-butyl-alpha-phenyl nitrone as a white solid melting at 70°-72° C. This is the nitrone described in Japanese Sho No. 59-11345.

Sources & evidence

ORD record
ord-4cea29d3563046168c242b9deb9efc7b
Source dataset
uspto-grants-1990_02
Patent number
US04898901

Reaction notes

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