反应详情

The product of step (b) (4.1 g) was dissolved in ethyl acetate (130 ml) and the stirred solution cooled to -10°. An ice cold solution of m-chloroperbenzoic acid (2.77 g of 95%) in ethyl acetate (20 ml) was added. The resulting solution was stirred for 40 minutes, and then washed with sodium bicarbonate solution, water and brine, dried and evaporated. The residue was purified by flash chromatography to produce a colourless foam. The foam was subjected to high vacuum which afforded 3.18 g of the title compound.

1. temperaturethe stirred solution cooled to -10°
2. washwashed with sodium bicarbonate solution, water and brine
3. customdried
4. customevaporated
5. customThe residue was purified by flash chromatography
6. customto produce a colourless foam