Sodium ion → 6-acetyl-9-(2-fluorobenzyl)-2-(2-fluorophenyl)-7,8,9,10-tetrahydro-imidazo[1,2-c]pyrido[3,4-e] pyrimidin-5(6H)-one

HRID 1200512Notes

Reaction equation

HRID 1200512 reaction equation
[CH3:32][C:33]([Cl:34])=[O:35].[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[F:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][c:7]3[c:8]4[n:9]([c:10](=[O:15])[nH:11][c:12]3[CH2:13][CH2:14]2)[cH:16][c:17](-[c:19]2[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]2)[n:18]4)[cH:26][cH:27][cH:28][cH:29]1.[H-:30].[Na+:31].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[F:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][c:7]3[c:8]4[n:9]([c:10](=[O:15])[n:11]([C:33]([CH3:32])=[O:35])[c:12]3[CH2:13][CH2:14]2)[cH:16][c:17](-[c:19]2[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]2)[n:18]4)[cH:26][cH:27][cH:28][cH:29]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6367Acetyl chlorideHCID 8857Ethyl AcetateHCID 166653HydrideHCID 11761005HCID 11761005, compound

Product 1

HCID 190143566-acetyl-9-(2-fluorobenzyl)-2-(2-fluorophenyl)-7,8,9,10-tetrahydro-imidazo[1,2-c]pyrido[3,4-e] pyrimidin-5(6H)-one

Sources & evidence

ORD record
ord-4f08f00060ba4bab96e769ae1f8f4adc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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