Methanol → [5-(4-Chloro-benzyloxy)-4-methoxy-pyridin-2-yl]-methanol

HRID 1200630Notes

Reaction equation

HRID 1200630 reaction equation
[CH3:19][Si:20]([CH:21]=[N+:22]=[N-:23])([CH3:24])[CH3:25].[CH3:26][OH:27].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][c:8]2[c:9](=[O:16])[cH:10][c:11]([CH2:14][OH:15])[nH:12][cH:13]2)[cH:17][cH:18]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][c:8]2[c:9]([O:16][CH3:19])[cH:10][c:11]([CH2:14][OH:15])[n:12][cH:13]2)[cH:17][cH:18]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6228DimethylformamideHCID 8058HexaneHCID 167693TrimethylsilyldiazomethaneHCID 580875645-(4-chloro-benzyloxy)-2-hydroxymethyl-1H-pyridin-4-one

Product 1

HCID 58087092[5-(4-Chloro-benzyloxy)-4-methoxy-pyridin-2-yl]-methanol

Sources & evidence

ORD record
ord-97a13039562841dbb283b6b4ebabf89d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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