Dichloromethane → 2-[(1-Methyl-1-piperidin-4-ylethyl)sulfonyl]-6-(trifluoromethyl)pyridine

HRID 1201452Notes

Reaction equation

HRID 1201452 reaction equation
[CH3:1][C:2]([CH3:3])([S:4](=[O:5])(=[O:6])[c:7]1[n:8][c:9]([C:13]([F:14])([F:15])[F:16])[cH:10][cH:11][cH:12]1)[CH:17]1[CH2:18][CH2:19][N:20]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:21][CH2:22]1.[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[CH3:1][C:2]([CH3:3])([S:4](=[O:5])(=[O:6])[c:7]1[n:8][c:9]([C:13]([F:14])([F:15])[F:16])[cH:10][cH:11][cH:12]1)[CH:17]1[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8857Ethyl AcetateHCID 59447129Tert-butyl 4-(1-methyl-1-{[6-(trifluoromethyl)pyridin-2-yl]sulfonyl}ethyl)piperidine-1-carboxylate

Product 1

HCID 594474312-[(1-Methyl-1-piperidin-4-ylethyl)sulfonyl]-6-(trifluoromethyl)pyridine

Sources & evidence

ORD record
ord-00935a036e7046018c95c3b00ba30c0c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…