Nitrogen → 3-(3,4-dihydro-2H-quinoline-1-yl)pyridine-2-carbonitrile

HRID 1202075Notes

Reaction equation

HRID 1202075 reaction equation
[Br:9][c:10]1[c:11]([C:16]#[N:17])[n:12][cH:13][cH:14][cH:15]1.[C:3](=[O:4])([O-:5])[O-:6].[CH2:18]1[CH2:19][NH:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]2[CH2:27]1.[CH3:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[Cs+:7].[Cs+:8].[N:1]#[N:2].[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[c:37]3[c:61]([cH:62][cH:63][cH:64]2)[C:58]([CH3:59])([CH3:60])[c:40]2[c:39]([c:44]([P:45]([c:46]4[cH:47][cH:48][cH:49][cH:50][cH:51]4)[c:52]4[cH:53][cH:54][cH:55][cH:56][cH:57]4)[cH:43][cH:42][cH:41]2)[O:38]3)[cH:65][cH:66][cH:67][cH:68][cH:69]1>>[c:10]1([N:20]2[CH2:19][CH2:18][CH2:27][c:26]3[c:21]2[cH:22][cH:23][cH:24][cH:25]3)[c:11]([C:16]#[N:17])[n:12][cH:13][cH:14][cH:15]1

Participants

8

Reactant 7

HCID 947NitrogenHCID 1140TolueneHCID 19660Carbonate IonHCID 694601,2,3,4-TetrahydroquinolineHCID 104967Cesium cation2×HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 8176943-Bromopyridine-2-carbonitrile

Product 1

HCID 672715793-(3,4-dihydro-2H-quinoline-1-yl)pyridine-2-carbonitrile

Sources & evidence

ORD record
ord-b98e338c3acd407e925d9f59cc8d7783
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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