Dimethylformamide → 1-[bis(4-chlorophenyl)methyl]-3-{(methylsulfonyl)[3-(N-piperidylcarbamoyl)phenyl]methylene}azetidine
Reaction equation
[CH3:52][N:53]([CH3:54])[CH:55]=[O:56].[CH3:57][CH2:58][O:59][C:60](=[O:61])[CH3:62].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][C:11](=[C:13]([c:14]3[cH:15][c:16]([C:20](=[O:21])[O:22][c:23]4[c:24]([F:25])[c:26]([F:27])[c:28]([F:29])[c:30]([F:31])[c:32]4[F:33])[cH:17][cH:18][cH:19]3)[S:34](=[O:35])(=[O:36])[CH3:37])[CH2:12]2)[c:38]2[cH:39][cH:40][c:41]([Cl:44])[cH:42][cH:43]2)[cH:6][cH:7]1.[NH2:45][N:46]1[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][C:11](=[C:13]([c:14]3[cH:15][c:16]([C:20](=[O:21])[NH:45][N:46]4[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51]4)[cH:17][cH:18][cH:19]3)[S:34](=[O:35])(=[O:36])[CH3:37])[CH2:12]2)[c:38]2[cH:39][cH:40][c:41]([Cl:44])[cH:42][cH:43]2)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-384695dc7b2e43fb9b61a8b3816cef8c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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