Water → Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxylate

HRID 1203032Notes

Reaction equation

HRID 1203032 reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[N:1](=[N+:2]=[N-:3])[CH2:4][c:5]1[c:6]([CH3:27])[n:7][c:8]2[n:9]([c:10]1-[c:11]1[c:12]([Cl:18])[cH:13][c:14]([Cl:17])[cH:15][cH:16]1)[cH:19][c:20]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[n:21]2.[OH2:52].[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[NH2:1][CH2:4][c:5]1[c:6]([CH3:27])[n:7][c:8]2[n:9]([c:10]1-[c:11]1[c:12]([Cl:18])[cH:13][c:14]([Cl:17])[cH:15][cH:16]1)[cH:19][c:20]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[n:21]2

Participants

5

Reactant 4

HCID 962WaterHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 46901747HCID 46901747, compound

Product 1

HCID 11559922Ethyl 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxylate

Sources & evidence

ORD record
ord-664b3e7953f94b6cb8d2d0a828b10ffd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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