Bromide ion → Ibuprofen, (+-)-

HRID 1203282Notes

Reaction equation

HRID 1203282 reaction equation
[Br-:10].[Br:4][CH:5]([C:6](=[O:7])[OH:8])[CH3:9].[CH2:11]([CH:12]([CH3:13])[CH3:14])[c:15]1[cH:16][cH:17][c:18]([Mg+:21])[cH:19][cH:20]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[Cl-:1].[Cl-:3].[Mg+2:2]>>[CH:5]([C:6](=[O:7])[OH:8])([CH3:9])[c:18]1[cH:17][cH:16][c:15]([CH2:11][CH:12]([CH3:13])[CH3:14])[cH:20][cH:19]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 312Chloride2×HCID 888Magnesium CationHCID 8028TetrahydrofuranHCID 117292-Bromopropionic acidHCID 178440989HCID 178440989, compound

Product 1

HCID 3672Ibuprofen, (+-)-

Sources & evidence

ORD record
ord-a444291266d34aaeba32b814bc55d6f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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