Dimethylformamide → 5-(4-Methyl-1H-imidazol-1-yl)pyridin-2-amine

HRID 1203518Notes

Reaction equation

HRID 1203518 reaction equation
[Br:13][c:14]1[cH:15][cH:16][c:17]([NH2:20])[n:18][cH:19]1.[C:1](=[O:2])([O-:3])[O-:4].[CH3:7][c:8]1[n:9][cH:10][nH:11][cH:12]1.[Cs+:5].[Cs+:6].[Cu:21][I:22].[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[CH3:7][c:8]1[n:9][cH:10][n:11](-[c:14]2[cH:15][cH:16][c:17]([NH2:20])[n:18][cH:19]2)[cH:12]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 706222-Amino-5-bromopyridineHCID 104967Cesium cation2×HCID 178418800HCID 178418800, compound

Product 1

HCID 575128615-(4-Methyl-1H-imidazol-1-yl)pyridin-2-amine

Sources & evidence

ORD record
ord-b6e3c213b7f24c47b24914a2860120b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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