Tetrahydrofuran → 2-tert-Butyl-1-(cyclohexylmethyl)-N-methyl-1H-benzimidazol-5-amine
Reaction equation
[Al+3:27].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:1][N:2]([C:3](=[O:4])[O-:5])[c:6]1[cH:7][c:8]2[c:9]([n:10]([CH2:17][CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:11]([C:13]([CH3:14])([CH3:15])[CH3:16])[n:12]2)[cH:24][cH:25]1.[H-:26].[H-:29].[H-:30].[H-:31].[Li+:28]>>[CH3:1][NH:2][c:6]1[cH:7][c:8]2[c:9]([n:10]([CH2:17][CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:11]([C:13]([CH3:14])([CH3:15])[CH3:16])[n:12]2)[cH:24][cH:25]1Participants
6
Sources & evidence
- ORD record
- ord-d66761496f594b9784f1574d7a3a4c75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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