Hydrochloric Acid → 4-(4-fluoro-3-(4-(pyrimidin-4-yloxy)piperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Reaction equation
[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[Cl:36][c:37]1[n:38][cH:39][n:40][cH:41][cH:42]1.[ClH:35].[F:7][c:8]1[c:9]([C:26](=[O:27])[N:28]2[CH2:29][CH2:30][CH:31]([OH:34])[CH2:32][CH2:33]2)[cH:10][c:11]([CH2:12][c:13]2[n:14][nH:15][c:16](=[O:23])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[cH:24][cH:25]1.[Na+:6].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[F:7][c:8]1[c:9]([C:26](=[O:27])[N:28]2[CH2:29][CH2:30][CH:31]([O:34][c:37]3[n:38][cH:39][n:40][cH:41][cH:42]3)[CH2:32][CH2:33]2)[cH:10][c:11]([CH2:12][c:13]2[n:14][nH:15][c:16](=[O:23])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[cH:24][cH:25]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2ba21ced8743406485a5571985a33514
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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