Toluene → 4-Chloro-6-(2-morpholinopyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazine

HRID 1204072Notes

Reaction equation

[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][cH:9][cH:10][c:11](-[c:13]3[cH:14][c:15]4[c:16]([OH:22])[n:17][cH:18][n:19][n:20]4[cH:21]3)[cH:12]2)[CH2:5][CH2:6]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27].[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32]>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][cH:9][cH:10][c:11](-[c:13]3[cH:14][c:15]4[c:16]([Cl:30])[n:17][cH:18][n:19][n:20]4[cH:21]3)[cH:12]2)[CH2:5][CH2:6]1

Participants

Reactant 4

HCID 1140Toluene

HCID 6228Dimethylformamide

HCID 24813Phosphorus oxychloride

HCID 178518236HCID 178518236, compound

Product 1

HCID 210816804-Chloro-6-(2-morpholinopyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazine

Sources & evidence

ORD record: ord-36e5f8bcc465445c8c6857206f54910e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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