Tetrahydrofuran → N-(4-(3-(4-(Bis(4-methoxybenzyl)amino)-6-methyl-1,3,5-triazin-2-YL)-5-((4-(methylsulfonyl)piperazin-1-YL)methyl)pyridin-2-ylamino)phenyl)acetamide
Reaction equation
[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:12][Si:13]([N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[F:22][c:23]1[n:24][cH:25][c:26]([CH2:55][N:56]2[CH2:57][CH2:58][N:59]([S:62](=[O:63])(=[O:64])[CH3:65])[CH2:60][CH2:61]2)[cH:27][c:28]1-[c:29]1[n:30][c:31]([N:36]([CH2:37][c:38]2[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]2)[CH2:46][c:47]2[cH:48][cH:49][c:50]([O:53][CH3:54])[cH:51][cH:52]2)[n:32][c:33]([CH3:35])[n:34]1.[Li+:21].[NH2:1][c:2]1[cH:3][cH:4][c:5]([NH:6][C:7]([CH3:8])=[O:9])[cH:10][cH:11]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([NH:6][C:7]([CH3:8])=[O:9])[cH:10][cH:11]1)[c:23]1[n:24][cH:25][c:26]([CH2:55][N:56]2[CH2:57][CH2:58][N:59]([S:62](=[O:63])(=[O:64])[CH3:65])[CH2:60][CH2:61]2)[cH:27][c:28]1-[c:29]1[n:30][c:31]([N:36]([CH2:37][c:38]2[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]2)[CH2:46][c:47]2[cH:48][cH:49][c:50]([O:53][CH3:54])[cH:51][cH:52]2)[n:32][c:33]([CH3:35])[n:34]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-394b878834234e518b4deb7c475b7fe2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…