1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → tert-butyl N-[3-hydroxy-1-phenyl-4-[(5-prop-1-en-2-ylpyridine-3-carbonyl)amino]butan-2-yl]carbamate

HRID 1204871Notes

Reaction equation

HRID 1204871 reaction equation
[CH2:1]=[C:2]([CH3:3])[c:4]1[cH:5][n:6][cH:7][c:8]([C:9](=[O:10])[OH:11])[cH:12]1.[CH3:13][CH2:14][N:15]=[C:16]=[N:17][CH2:18][CH2:19][CH2:20][N:21]([CH3:22])[CH3:23].[CH:54]([N:55]([CH2:56][CH3:57])[CH:58]([CH3:59])[CH3:60])([CH3:61])[CH3:62].[NH2:34][CH2:35][CH:36]([CH:37]([CH2:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1)[NH:45][C:46]([O:47][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:52])[OH:53].[OH:24][n:25]1[c:26]2[c:27]([cH:28][cH:29][cH:30][cH:31]2)[n:32][n:33]1>>[CH2:1]=[C:2]([CH3:3])[c:4]1[cH:5][n:6][cH:7][c:8]([C:9](=[O:11])[NH:34][CH2:35][CH:36]([CH:37]([CH2:38][c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[NH:45][C:46]([O:47][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:52])[OH:53])[cH:12]1

Participants

6

Reactant 5

HCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 11065838tert-butyl N-(4-amino-3-hydroxy-1-phenylbutan-2-yl)carbamateHCID 686704595-(Prop-1-en-2-yl)nicotinic acid

Product 1

HCID 141232495tert-butyl N-[3-hydroxy-1-phenyl-4-[(5-prop-1-en-2-ylpyridine-3-carbonyl)amino]butan-2-yl]carbamate

Sources & evidence

ORD record
ord-1dea6258c2444e6db043a8bce9b265ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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