Dichloromethane → Ethyl 3-(2-acetyl-2,3-dihydro-1h-spiro[isoquinoline-4,4'-piperidine]-1'-yl)-8-azabicyclo[3.2.1]octane-8-carboxylate
Reaction equation
[CH3:29][C:30]([Cl:31])=[O:32].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[Cl:40][CH2:41][Cl:42].[N:1]1([CH:16]2[CH2:17][CH:18]3[CH2:19][CH2:20][CH:21]([CH2:22]2)[N:23]3[C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:2][CH2:3][C:4]2([CH2:5][NH:6][CH2:7][c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]32)[CH2:14][CH2:15]1>>[N:1]1([CH:16]2[CH2:17][CH:18]3[CH2:19][CH2:20][CH:21]([CH2:22]2)[N:23]3[C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:2][CH2:3][C:4]2([CH2:5][N:6]([C:30]([CH3:29])=[O:32])[CH2:7][c:8]3[cH:9][cH:10][cH:11][cH:12][c:13]32)[CH2:14][CH2:15]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-26cbc003a7714f25a30ca68e30d9c8cc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…