Tetrahydrofuran → 6-(3-Phenyl-5-trifluoromethyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester
Reaction equation
[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:18][O:19][C:20]([c:21]1[cH:22][n:23][c:24]([OH:27])[cH:25][cH:26]1)=[O:28].[O:48]=[C:49]([O:50][CH2:51][CH3:52])[N:53]=[N:54][C:55]([O:56][CH2:57][CH3:58])=[O:59].[c:1]1(-[c:7]2[n:8][o:9][c:10]([C:14]([F:15])([F:16])[F:17])[c:11]2[CH2:12][OH:13])[cH:2][cH:3][cH:4][cH:5][cH:6]1.[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[c:1]1(-[c:7]2[n:8][o:9][c:10]([C:14]([F:15])([F:16])[F:17])[c:11]2[CH2:12][O:13][c:24]2[n:23][cH:22][c:21]([C:20]([O:19][CH3:18])=[O:28])[cH:26][cH:25]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-dbaa185682204006a7bb54e121bbea85
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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