Dimethylformamide → Methyl 3-methyl-2-[[4-[4-[(3-methyl-4-pyridin-4-yl-1-benzofuran-2-carbonyl)amino]phenyl]phenyl]sulfonylamino]butanoate

HRID 1205533Notes

Reaction equation

HRID 1205533 reaction equation
[CH3:1][c:2]1[c:3]([C:17](=[O:18])[OH:19])[o:4][c:5]2[c:6]1[c:7](-[c:11]1[cH:12][cH:13][n:14][cH:15][cH:16]1)[cH:8][cH:9][cH:10]2.[CH3:20][O:21][C:22]([CH:23]([CH:24]([CH3:25])[CH3:26])[NH:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][cH:33][c:34](-[c:37]2[cH:38][cH:39][c:40]([NH2:43])[cH:41][cH:42]2)[cH:35][cH:36]1)=[O:44].[CH:72]([N:73]([CH2:74][CH3:75])[CH:76]([CH3:77])[CH3:78])([CH3:79])[CH3:80].[O:81]=[CH:82][N:83]([CH3:84])[CH3:85].[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[n:52]1([O:53][P+:54]([N:55]([CH3:56])[CH3:57])([N:58]([CH3:59])[CH3:60])[N:61]([CH3:62])[CH3:63])[c:64]2[cH:65][cH:66][cH:67][cH:68][c:69]2[n:70][n:71]1>>[CH3:1][c:2]1[c:3]([C:17](=[O:19])[NH:43][c:40]2[cH:39][cH:38][c:37](-[c:34]3[cH:33][cH:32][c:31]([S:28]([NH:27][CH:23]([C:22]([O:21][CH3:20])=[O:44])[CH:24]([CH3:25])[CH3:26])(=[O:29])=[O:30])[cH:36][cH:35]3)[cH:42][cH:41]2)[o:4][c:5]2[c:6]1[c:7](-[c:11]1[cH:12][cH:13][n:14][cH:15][cH:16]1)[cH:8][cH:9][cH:10]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 124335Benzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 66909162Methyl 2-[[4-(4-aminophenyl)phenyl]sulfonylamino]-3-methylbutanoateHCID 687150813-Methyl-4-pyridin-4-yl-benzofuran-2-carboxylic acid

Product 1

HCID 68715326Methyl 3-methyl-2-[[4-[4-[(3-methyl-4-pyridin-4-yl-1-benzofuran-2-carbonyl)amino]phenyl]phenyl]sulfonylamino]butanoate

Sources & evidence

ORD record
ord-cb2591e21e4e40eba100ce8c34209481
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…