Tetrahydrofuran → 2-(3-(1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)-2-methylpropan-1-amine
Reaction equation
[Al+3:22].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[nH:1]1[n:2][cH:3][c:4]2[c:5]1[n:6][cH:7][cH:8][c:9]2-[c:10]1[cH:11][c:12]([C:16]([C:17]#[N:18])([CH3:19])[CH3:20])[cH:13][cH:14][cH:15]1>>[nH:1]1[n:2][cH:3][c:4]2[c:5]1[n:6][cH:7][cH:8][c:9]2-[c:10]1[cH:11][c:12]([C:16]([CH2:17][NH2:18])([CH3:19])[CH3:20])[cH:13][cH:14][cH:15]1Participants
6
Sources & evidence
- ORD record
- ord-f6fdc2e2c3b44535bc345bd99938d88f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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