Tetrahydrofuran → Tert-butyl 4-[(3-acetylphenyl)carbamoylamino]-3-[3-[(4-fluorophenyl)methyl]piperidine-1-carbonyl]piperidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:15](=[O:16])[N:17]2[CH2:18][CH:19]([CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH2:20][CH2:21][CH2:22]2)[CH:11]([NH2:14])[CH2:12][CH2:13]1.[C:38]([CH3:39])(=[O:40])[c:41]1[cH:42][c:43]([N:47]=[C:48]=[O:49])[cH:44][cH:45][cH:46]1.[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:15](=[O:16])[N:17]2[CH2:18][CH:19]([CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH2:20][CH2:21][CH2:22]2)[CH:11]([NH:14][C:48]([NH:47][c:43]2[cH:42][c:41]([C:38]([CH3:39])=[O:40])[cH:46][cH:45][cH:44]2)=[O:49])[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-22f87443dde04f0e9b2f858745149a6c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…