Tetrahydrofuran → 1-[4-(4-Chloro-3-methoxy-phenyl)-piperazin-1-yl]-2-(3-morpholin-4-yl-pyrazolo[3,4-b]pyridin-1-yl)-ethanone
Reaction equation
[C:35](=[O:36])([O-:37])[O-:38].[CH2:29]1[CH2:30][O:31][CH2:32][CH2:33][NH:34]1.[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:1][c:2]1[c:3]([O:27][CH3:28])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14]([CH2:15][n:16]3[n:17][c:18]([I:25])[c:19]4[c:20]3[n:21][cH:22][cH:23][cH:24]4)=[O:26])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[Cs+:39].[Cs+:40].[O:54]=[C:55]([CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1.[O:72]=[C:73]([CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1)[CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1.[O:90]=[C:91]([CH:92]=[CH:93][c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1)[CH:100]=[CH:101][c:102]1[cH:103][cH:104][cH:105][cH:106][cH:107]1.[Pd:52].[Pd:53]>>[Cl:1][c:2]1[c:3]([O:27][CH3:28])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14]([CH2:15][n:16]3[n:17][c:18]([N:34]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[c:19]4[c:20]3[n:21][cH:22][cH:23][cH:24]4)=[O:26])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-dc63951cfa6f47129bcd6ef388030166
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…