Tetrahydrofuran → Methyl 3-[1-(6-chloropyridazin-3-yl)-2-oxo-4-(trimethylsilyl)but-3-yn-1-yl]-4-methoxybenzoate
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:22][Si:23]([N-:24][Si:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30].[CH3:31][Si:32]([C:33]#[C:34][C:35](=[O:36])[O:37][CH2:38][CH3:39])([CH3:40])[CH3:41].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][c:9]2[cH:10][c:11]([C:12](=[O:13])[O:14][CH3:15])[cH:16][cH:17][c:18]2[O:19][CH3:20])[n:6][n:7]1.[Li+:21]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([c:9]2[cH:10][c:11]([C:12](=[O:13])[O:14][CH3:15])[cH:16][cH:17][c:18]2[O:19][CH3:20])[C:35]([C:34]#[C:33][Si:32]([CH3:31])([CH3:40])[CH3:41])=[O:36])[n:6][n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f86b288baa634bceae61281cd946e493
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…