Tetrahydrofuran → 2-Cyclopropyl-2-(4-chlorophenyl)ethanol

HRID 1207267Notes

Reaction equation

HRID 1207267 reaction equation
[Al+3:24].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[N:11]2[CH:12]([CH:13]([CH3:14])[CH3:15])[CH2:16][O:17][C:18]2=[O:19])[CH:20]2[CH2:21][CH2:22]2)[cH:6][cH:7]1.[H-:23].[H-:26].[H-:27].[H-:28].[Li+:25].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][OH:10])[CH:20]2[CH2:21][CH2:22]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 156167093-[2-(4-Chlorophenyl)-2-cyclopropylacetyl]-4-propan-2-yl-1,3-oxazolidin-2-one

Product 1

HCID 156167072-Cyclopropyl-2-(4-chlorophenyl)ethanol

Sources & evidence

ORD record
ord-90993706f4384f6b86c4f56a755c457d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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