Methanol → 6-[4-[4-(Benzyloxy)phenoxy]piperidin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
Reaction equation
[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[CH3:74][OH:75].[F:15][C:16]([c:17]1[n:18][n:19][c:20]2[n:21]1[n:22][c:23]([N:26]1[CH2:27][CH2:28][CH:29]([OH:32])[CH2:30][CH2:31]1)[cH:24][cH:25]2)([F:33])[F:34].[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[OH:35][c:36]1[cH:37][cH:38][c:39]([O:40][CH2:41][c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[cH:48][cH:49]1.[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1>>[F:15][C:16]([c:17]1[n:18][n:19][c:20]2[n:21]1[n:22][c:23]([N:26]1[CH2:27][CH2:28][CH:29]([O:32][c:36]3[cH:37][cH:38][c:39]([O:40][CH2:41][c:42]4[cH:43][cH:44][cH:45][cH:46][cH:47]4)[cH:48][cH:49]3)[CH2:30][CH2:31]1)[cH:24][cH:25]2)([F:33])[F:34]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9ffad8a9655d4e37861c9e215d6c9e18
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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