Hydrochloric Acid → N-(2-Chloro-4-{[6-methoxy-7-(3-pyridyl-methoxy)-4-quinolyl]oxy}phenyl)-N'-(2,4-difluorophenyl)-urea
Reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[CH3:49][N:50]([CH3:51])[CH:52]=[O:53].[Cl:1][c:2]1[c:3]([NH:22][C:23](=[O:24])[NH:25][c:26]2[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]2)[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([OH:21])[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:7]1.[ClH:40].[K+:38].[K+:39].[cH:41]1[c:42]([CH2:47][Cl:48])[cH:43][cH:44][cH:45][n:46]1>>[Cl:1][c:2]1[c:3]([NH:22][C:23](=[O:24])[NH:25][c:26]2[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]2)[cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:47][c:42]4[cH:41][n:46][cH:45][cH:44][cH:43]4)[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-30af8f391a7843ec95e877b42590f26f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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