Acetate → 2-Cyano-α-(ethoxymethylene)-5-fluorobenzeneacetonitrile

HRID 1208332Notes

Reaction equation

HRID 1208332 reaction equation
[Br:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([F:10])[cH:9]1.[C:32]([O-:33])(=[O:34])[CH3:35].[C:37]([O-:38])(=[O:39])[CH3:40].[CH2:11]([CH3:12])[O:13][CH:14]=[CH:15][C:16]#[N:17].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[Pd+2:36]>>[c:2]1([C:15](=[CH:14][O:13][CH2:11][CH3:12])[C:16]#[N:17])[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([F:10])[cH:9]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 1140TolueneHCID 8471TriethylamineHCID 436013-Ethoxy-2-propenenitrileHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 1189392-Bromo-4-fluorobenzonitrile

Product 1

HCID 675306412-Cyano-α-(ethoxymethylene)-5-fluorobenzeneacetonitrile

Sources & evidence

ORD record
ord-001949781e744a15a07aea171bc2a0ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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