Dichloromethane → N,N-bis(4-methoxybenzyl)-4-(2-(2-methoxypyrimidin-5-ylamino)-5-((4-(methylsulfonyl)piperazin-1-yl)methyl)pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine
Reaction equation
[CH3:63][CH2:64][N:65]([CH2:66][CH3:67])[CH2:68][CH3:69].[CH3:70][S:71]([Cl:72])(=[O:73])=[O:74].[CH3:8][O:9][c:10]1[cH:11][cH:12][c:13]([CH2:14][N:15]([c:16]2[n:17][c:18](-[c:23]3[cH:24][c:25]([CH2:38][N:39]4[CH2:40][CH2:41][N:42]([C:45]([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])=[O:51])[CH2:43][CH2:44]4)[cH:26][n:27][c:28]3[NH:29][c:30]3[cH:31][n:32][c:33]([O:36][CH3:37])[n:34][cH:35]3)[n:19][c:20]([CH3:22])[n:21]2)[CH2:52][c:53]2[cH:54][cH:55][c:56]([O:59][CH3:60])[cH:57][cH:58]2)[cH:61][cH:62]1.[Cl:75][CH2:76][Cl:77].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[CH3:8][O:9][c:10]1[cH:11][cH:12][c:13]([CH2:14][N:15]([c:16]2[n:17][c:18](-[c:23]3[cH:24][c:25]([CH2:38][N:39]4[CH2:40][CH2:41][N:42]([S:71]([CH3:70])(=[O:73])=[O:74])[CH2:43][CH2:44]4)[cH:26][n:27][c:28]3[NH:29][c:30]3[cH:31][n:32][c:33]([O:36][CH3:37])[n:34][cH:35]3)[n:19][c:20]([CH3:22])[n:21]2)[CH2:52][c:53]2[cH:54][cH:55][c:56]([O:59][CH3:60])[cH:57][cH:58]2)[cH:61][cH:62]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9f74b6e320a94f1bb3524d8cf03087ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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